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Ccl4 3d Model. Carbon tetrachloride ccl4 cid 5943 structure chemical names physical and chemical properties classification patents literature biological activities. It has practically no flammability at lower temperatures.
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One of the first animal models used for nafld drug discovery was the carbon tetrachloride ccl4 model introduced in the 1970s. Ccl4 in olive oil was administered to strain a j mice three times per week by oral gavage. The carbon tetrachloride ccl4 induced mouse model has been historically relied upon to study liver injury and regeneration.
A quick explanation of the molecular geometry of ccl4 including a description of the ccl4 bond angles looking at the ccl4 lewis structure we can see that the.
We exposed mice to ccl4 to assess whether egf and cd133 hscs are up regulated in chronically injured liver. It has practically no flammability at lower temperatures. One of the first animal models used for nafld drug discovery was the carbon tetrachloride ccl4 model introduced in the 1970s. There are many ways to induce nafld nash for preclinical rodent modeling methods include dietary manipulation employing high fat high cholesterol high fructose methionine choline deficient diets or combinations of the above chemotoxic agent induction and acute liver injury models.
